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Morikazu Onji Selected Research

Hepatitis B Core Antigens

1/2018Treatment of chronic hepatitis B naïve patients with a therapeutic vaccine containing HBs and HBc antigens (a randomized, open and treatment controlled phase III clinical trial).
10/2012Strong and multi-antigen specific immunity by hepatitis B core antigen (HBcAg)-based vaccines in a murine model of chronic hepatitis B: HBcAg is a candidate for a therapeutic vaccine against hepatitis B virus.
8/2012Long-term outcome of Japanese patients with type 1 autoimmune hepatitis.
8/2010Impaired dendritic cell functions disrupt antigen-specific adaptive immune responses in mice with nonalcoholic fatty liver disease.
5/2003The effects of hepatitis B virus core promoter mutations on hepatitis B core antigen distribution in hepatocytes as detected by laser-assisted microdissection.

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Morikazu Onji Research Topics

Disease

39Hepatocellular Carcinoma (Hepatoma)
04/2013 - 03/2002
29Neoplasms (Cancer)
03/2014 - 03/2003
18Hepatitis
08/2015 - 01/2002
17Infections
01/2016 - 01/2004
15Chronic Hepatitis C
01/2013 - 05/2002
13Fibrosis (Cirrhosis)
06/2014 - 05/2003
13Liver Cirrhosis (Hepatic Cirrhosis)
07/2012 - 05/2003
12Liver Diseases (Liver Disease)
07/2018 - 01/2002
12Chronic Hepatitis B
01/2018 - 02/2003
12Chronic Hepatitis (Chronic Active Hepatitis)
09/2011 - 01/2002
9Biliary Liver Cirrhosis (Primary Biliary Cirrhosis)
08/2015 - 04/2002
8Autoimmune Hepatitis
06/2015 - 04/2002
8Insulin Resistance
06/2013 - 01/2004
7Hypertension (High Blood Pressure)
06/2017 - 01/2016
7Type 2 Diabetes Mellitus (MODY)
01/2017 - 05/2007
7Inflammation (Inflammations)
06/2013 - 01/2003
6Diabetic Nephropathies (Diabetic Nephropathy)
01/2017 - 01/2014
6Non-alcoholic Fatty Liver Disease
01/2016 - 08/2010
6Neoplasm Metastasis (Metastasis)
01/2013 - 03/2002
5Ascites
07/2018 - 06/2005
5Dyslipidemias (Dyslipidemia)
06/2017 - 01/2016
4Diabetic Retinopathy (Retinopathy, Diabetic)
06/2017 - 01/2016
4Stroke (Strokes)
06/2017 - 01/2016
4Diabetes Mellitus
07/2016 - 05/2007
4Chemical and Drug Induced Liver Injury
12/2014 - 01/2002
4Graves Disease (Basedow Disease)
01/2013 - 04/2003
4Hepatitis C
04/2009 - 05/2002
3Pancreatic Neoplasms (Pancreatic Cancer)
01/2019 - 01/2013
3Diabetic Neuropathies (Diabetic Neuropathy)
11/2016 - 01/2016
3Jaundice (Icterus)
08/2015 - 01/2003
3Obesity
01/2015 - 03/2013
3Disease Progression
06/2014 - 06/2005
3Thrombocytopenia (Thrombopenia)
03/2011 - 09/2008
3Virus Diseases (Viral Diseases)
09/2007 - 02/2003
3Liver Failure
05/2007 - 05/2005
2Pain (Aches)
04/2022 - 01/2006
2Cicatrix (Scar)
07/2018 - 06/2009
2Coronary Artery Disease (Coronary Atherosclerosis)
11/2016 - 01/2016
2Ischemic Stroke
09/2016 - 07/2016
2Heart Diseases (Heart Disease)
09/2016 - 07/2016
2Colitis
06/2013 - 03/2012
2Metabolic Syndrome (Dysmetabolic Syndrome X)
03/2013 - 01/2012
2Hyperthyroidism
01/2013 - 02/2004

Drug/Important Bio-Agent (IBA)

20AntigensIBA
01/2018 - 04/2002
13InterferonsIBA
01/2018 - 05/2002
12VaccinesIBA
01/2018 - 01/2004
11Hepatitis B Surface Antigens (HBsAg)FDA Link
01/2018 - 05/2003
9Antiviral Agents (Antivirals)IBA
11/2012 - 06/2004
8DNA (Deoxyribonucleic Acid)IBA
01/2010 - 02/2003
7Proteins (Proteins, Gene)FDA Link
07/2018 - 11/2003
7Ribavirin (Virazole)FDA LinkGeneric
02/2011 - 01/2003
6AlbuminsIBA
07/2018 - 06/2005
6Insulin (Novolin)FDA Link
06/2017 - 04/2011
6Glycated Hemoglobin (Glycosylated Hemoglobin)IBA
06/2017 - 01/2016
6Messenger RNA (mRNA)IBA
03/2014 - 04/2004
6B-Cell Activating FactorIBA
06/2013 - 08/2011
6Pharmaceutical PreparationsIBA
01/2012 - 11/2003
6RNA (Ribonucleic Acid)IBA
01/2010 - 02/2003
5Hepatitis B Core AntigensIBA
01/2018 - 05/2003
5BilirubinIBA
06/2015 - 01/2006
5Branched-Chain Amino AcidsIBA
06/2014 - 07/2005
5Alanine Transaminase (SGPT)IBA
06/2012 - 01/2002
5alpha-Fetoproteins (alpha-Fetoprotein)IBA
01/2012 - 05/2003
5Lamivudine (Epivir)FDA Link
07/2007 - 05/2003
4AutoantibodiesIBA
08/2015 - 04/2003
4Adrenal Cortex Hormones (Corticosteroids)IBA
06/2015 - 02/2007
4CytokinesIBA
01/2015 - 01/2005
4Transaminases (Aminotransferases)IBA
12/2014 - 01/2002
4Amino AcidsFDA Link
06/2014 - 01/2004
4Biomarkers (Surrogate Marker)IBA
08/2013 - 12/2011
4Glucose (Dextrose)FDA LinkGeneric
03/2013 - 01/2004
4Ursodeoxycholic Acid (Urso)FDA LinkGeneric
09/2011 - 06/2008
4Ethanol (Ethyl Alcohol)IBA
05/2011 - 03/2003
4EnzymesIBA
01/2006 - 05/2002
4ChemokinesIBA
01/2005 - 05/2002
3CreatinineIBA
07/2016 - 01/2014
3Hemoglobins (Hemoglobin)IBA
01/2016 - 05/2007
3Prothrombin (Factor II)IBA
12/2014 - 04/2013
3Tumor Biomarkers (Tumor Markers)IBA
04/2013 - 11/2005
3Antinuclear AntibodiesIBA
09/2011 - 02/2007
3Fluorouracil (Carac)FDA LinkGeneric
08/2011 - 09/2008
3Aspartate Aminotransferases (Aspartate Transaminase)IBA
02/2011 - 05/2002
3perfluorobutane (AI 700)IBA
09/2010 - 06/2009
3SonazoidIBA
09/2010 - 01/2010
3Hepatitis B e AntigensIBA
01/2010 - 04/2004
3Interferon-alpha (Interferon Alfa)IBA
07/2008 - 01/2003
2AntibodiesIBA
12/2014 - 04/2013
2Dihydrotachysterol (AT 10)IBA
08/2013 - 03/2011
2SteroidsIBA
06/2013 - 03/2007
2Carbonic Anhydrase IIBA
06/2013 - 03/2012
2acarboxyprothrombin (PIVKA)IBA
04/2013 - 11/2005
2Immunoglobulin G (IgG)IBA
03/2013 - 09/2011
2AdipokinesIBA
03/2013 - 10/2011
2Small Interfering RNA (siRNA)IBA
01/2013 - 08/2011

Therapy/Procedure

57Therapeutics
01/2018 - 01/2002
13Radiofrequency Ablation
06/2011 - 09/2002
6Drug Therapy (Chemotherapy)
08/2013 - 01/2006
4Immunotherapy
11/2012 - 10/2003
4Liver Transplantation
04/2009 - 02/2003
3Splenectomy
01/2012 - 09/2008